Hepatocyte Viability and Adenosine Triphosphate Content Decrease Linearly Over Time During Conventional Cold Storage of Rat Liver Grafts

Fluorometric study of the viability of rat liver grafts after simple cold storage with UW solution versus Euro-Collins solution.

Proton movements and adenosine triphosphate synthesis in rat liver mitochondria.

In a previous communication (Archbold et al., 1974) we have described experiments the results of which are not readily reconciled with some aspects of the chemiosmotic hypothesis. Our interpretation required a distinction between the distributive nature ofelectroneutral (EN) and eiectrogenic (EG) proton movements across the mitochondria1 inner membrane. This distinction has not been made hither...

Adenosine triphosphate content of preimplantation mouse embryos.

The utilization of energy substrates by preimplantation mouse embryos undergoes several changes during development in vitro (Brinster, 1965a, b) but very little is known about the level of high-energy containing compounds, such as ATP at these stages. In the present study, the content ofATP in freshly collected preimplantation mouse embryos has been measured. For each estimation, fifty to 150 e...

Optimizing Co2 Enhances Chondrocyte Viability during Cold Storage

INTRODUCTION: Successful repair of full thickness defects to articular cartilage remains a clinical and scientific challenge. The use of fresh osteochondral allografts to replace damaged articular cartilage with healthy tissues harvested from human cadavers is a viable treatment option. Allografts are stored at 4C prior to transplantation to await final culture results that can take two to thre...

Adenosine triphosphate: adenosine monophosphate phosphotransferase isozymes in rat liver and hepatomas.